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Designing an irreversible metabolic switch for scalable induction of microbial chemical production

Bacteria can be harnessed to synthesise high-value chemicals. A promising strategy for increasing productivity uses inducible control systems to switch metabolism from growth to chemical synthesis once a large population of cell factories are generated. However, use of expensive chemical inducers li...

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Detalles Bibliográficos
Autores principales: Mannan, Ahmad A., Bates, Declan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187666/
https://www.ncbi.nlm.nih.gov/pubmed/34103495
http://dx.doi.org/10.1038/s41467-021-23606-x