PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis

AKT is involved in a number of key cellular processes including cell proliferation, apoptosis and metabolism. Hyperactivation of AKT is associated with many pathological conditions, particularly cancers. Emerging evidence indicates that arginine methylation is involved in modulating AKT signaling pa...

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Detalles Bibliográficos
Autores principales: Yin, Shasha, Liu, Liu, Brobbey, Charles, Palanisamy, Viswanathan, Ball, Lauren E., Olsen, Shaun K., Ostrowski, Michael C., Gan, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187744/
https://www.ncbi.nlm.nih.gov/pubmed/34103528
http://dx.doi.org/10.1038/s41467-021-23833-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187744/
https://www.ncbi.nlm.nih.gov/pubmed/34103528
http://dx.doi.org/10.1038/s41467-021-23833-2

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