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Force-Induced Autophagy in Periodontal Ligament Stem Cells Modulates M1 Macrophage Polarization via AKT Signaling

Autophagy, a lysosomal degradation pathway, serves as a protective cellular mechanism in maintaining cell and tissue homeostasis under mechanical stimulation. As the mechanosensitive cells, periodontal ligament stem cells (PDLSCs) play an important role in the force-induced inflammatory bone remodel...

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Detalles Bibliográficos
Autores principales: Jiang, Nan, He, Danqing, Ma, Yushi, Su, Junxiang, Wu, Xiaowen, Cui, Shengjie, Li, Zixin, Zhou, Yanheng, Yu, Huajie, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187804/
https://www.ncbi.nlm.nih.gov/pubmed/34124048
http://dx.doi.org/10.3389/fcell.2021.666631