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Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis

Synovial macrophages that are activated by cartilage fragments initiate synovitis, a condition that promotes hypertrophic changes in chondrocytes leading to cartilage degeneration in OA. In this study, we analyzed the molecular response of chondrocytes under condition of this type of stimulation to...

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Detalles Bibliográficos
Autores principales: Ebata, Taku, Terkawi, Mohamad Alaa, Hamasaki, Masanari, Matsumae, Gen, Onodera, Tomohiro, Aly, Mahmoud Khamis, Yokota, Shunichi, Alhasan, Hend, Shimizu, Tomohiro, Takahashi, Daisuke, Homan, Kentaro, Kadoya, Ken, Iwasaki, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187833/
https://www.ncbi.nlm.nih.gov/pubmed/34142066
http://dx.doi.org/10.1016/j.isci.2021.102643