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Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
Synovial macrophages that are activated by cartilage fragments initiate synovitis, a condition that promotes hypertrophic changes in chondrocytes leading to cartilage degeneration in OA. In this study, we analyzed the molecular response of chondrocytes under condition of this type of stimulation to...
Autores principales: | Ebata, Taku, Terkawi, Mohamad Alaa, Hamasaki, Masanari, Matsumae, Gen, Onodera, Tomohiro, Aly, Mahmoud Khamis, Yokota, Shunichi, Alhasan, Hend, Shimizu, Tomohiro, Takahashi, Daisuke, Homan, Kentaro, Kadoya, Ken, Iwasaki, Norimasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187833/ https://www.ncbi.nlm.nih.gov/pubmed/34142066 http://dx.doi.org/10.1016/j.isci.2021.102643 |
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