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Antidiabetic Agent DPP-4i Facilitates Murine Breast Cancer Metastasis by Oncogenic ROS-NRF2-HO-1 Axis via a Positive NRF2-HO-1 Feedback Loop

Cancer has been as one of common comorbidities of diabetes. Long-term antidiabetic treatment may potentially exert uncertain impacts on diabetic patients with cancer including breast cancer (BC). Dipeptidyl peptidase-4 inhibitors (DPP-4i) are currently recommended by the AACE as first-line hypoglyce...

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Detalles Bibliográficos
Autores principales: Li, Rui, Zeng, Xin, Yang, Meihua, Xu, Xiaohui, Feng, Jinmei, Bao, Liming, Xue, Bingqian, Wang, Xin, Huang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187865/
https://www.ncbi.nlm.nih.gov/pubmed/34123848
http://dx.doi.org/10.3389/fonc.2021.679816