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A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells

Cell therapy is witnessing a notable shift toward cell-free treatments based on paracrine factors, in particular, towards small extracellular vesicles (sEV), that mimic the functional effect of the parental cells. While numerous sEV-based applications are currently in advanced preclinical stages, th...

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Detalles Bibliográficos
Autores principales: Figueroa-Valdés, Aliosha I., de la Fuente, Catalina, Hidalgo, Yessia, Vega-Letter, Ana María, Tapia-Limonchi, Rafael, Khoury, Maroun, Alcayaga-Miranda, Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187876/
https://www.ncbi.nlm.nih.gov/pubmed/34124014
http://dx.doi.org/10.3389/fbioe.2021.619930