Cargando…

A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells

Cell therapy is witnessing a notable shift toward cell-free treatments based on paracrine factors, in particular, towards small extracellular vesicles (sEV), that mimic the functional effect of the parental cells. While numerous sEV-based applications are currently in advanced preclinical stages, th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Figueroa-Valdés, Aliosha I., de la Fuente, Catalina, Hidalgo, Yessia, Vega-Letter, Ana María, Tapia-Limonchi, Rafael, Khoury, Maroun, Alcayaga-Miranda, Francisca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187876/ https://www.ncbi.nlm.nih.gov/pubmed/34124014 http://dx.doi.org/10.3389/fbioe.2021.619930

Ejemplares similares

Oral Administration as a Potential Alternative for the Delivery of Small Extracellular Vesicles
por: Donoso-Meneses, Darío, et al.
Publicado: (2023)

The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro
por: Palamà, Maria Elisabetta Federica, et al.
Publicado: (2020)

Xeno-Free Spheroids of Human Gingiva-Derived Progenitor Cells for Bone Tissue Engineering
por: Shanbhag, Siddharth, et al.
Publicado: (2020)

Turning adversity into opportunity: Small extracellular vesicles as nanocarriers for tumor‐associated macrophages re‐education
por: Donoso‐Meneses, Dario, et al.
Publicado: (2022)

Development of a Chemically Defined Medium for in vitro Expansion of Primary Bovine Satellite Cells
por: Kolkmann, Anna M., et al.
Publicado: (2022)

Macromolecular crowding in animal component-free, xeno-free and foetal bovine serum media for human bone marrow mesenchymal stromal cell expansion and differentiation
por: Korntner, Stefanie H., et al.
Publicado: (2023)

Umbilical Cord‐Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
por: Matas, Jose, et al.
Publicado: (2018)

Growth Behavior of Selected Ustilaginaceae Fungi Used for Mannosylerythritol Lipid (MEL) Biosurfactant Production – Evaluation of a Defined Culture Medium
por: Beck, Alexander, et al.
Publicado: (2020)

Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome
por: Alcayaga-Miranda, Francisca, et al.
Publicado: (2023)

Effects of fermentation medium on cigar filler
por: Wen, Cai, et al.
Publicado: (2022)

Stem cell exosomes inhibit angiogenesis and tumor growth of oral squamous cell carcinoma
por: Rosenberger, Leonie, et al.
Publicado: (2019)

The Promising Potential of Menstrual Stem Cells for Antenatal Diagnosis and Cell Therapy
por: Khoury, Maroun, et al.
Publicado: (2014)

Compartmentalization and Transport in Synthetic Vesicles
por: Schmitt, Christine, et al.
Publicado: (2016)

Impact of Culture Medium on Cellular Interactions in in vitro Co-culture Systems
por: Vis, Michelle A. M., et al.
Publicado: (2020)

Developing Clostridia as Cell Factories for Short- and Medium-Chain Ester Production
por: Wang, Qingzhuo, et al.
Publicado: (2021)

Extracellular Vesicles in Musculoskeletal Pathologies and Regeneration
por: Herrmann, Marietta, et al.
Publicado: (2021)

Emerging technologies for engineering of extracellular vesicles
por: Zhou, Xin, et al.
Publicado: (2023)

Biological impact of xeno-free chemically defined cryopreservation medium on amniotic epithelial cells
por: Miki, Toshio, et al.
Publicado: (2016)

Microbial Culture in Minimal Medium With Oil Favors Enrichment of Biosurfactant Producing Genes
por: Araújo, W. J., et al.
Publicado: (2020)

Serum-Free Medium for Recombinant Protein Expression in Chinese Hamster Ovary Cells
por: Li, Weifeng, et al.
Publicado: (2021)

Effects of adding cocoa fermentation medium on cigar leaves in agricultural fermentation stage
por: Zong, Pengfei, et al.
Publicado: (2023)

Editorial: Bone and Cartilage Regeneration With Extracellular Vesicles
por: Tasso, Roberta, et al.
Publicado: (2021)

The potential therapeutic role of extracellular vesicles in osteoarthritis
por: Zhuang, Yu, et al.
Publicado: (2022)

Tracking tools of extracellular vesicles for biomedical research
por: Liu, Qisong, et al.
Publicado: (2022)

Native and engineered extracellular vesicles for wound healing
por: Lu, Shengli, et al.
Publicado: (2022)

Editorial: Engineered extracellular vesicles for tissue repairing
por: Yu, Shiyi, et al.
Publicado: (2023)

Prospective applications of extracellular vesicle-based therapies in regenerative medicine: implications for the use of dental stem cell-derived extracellular vesicles
por: Wang, Wenhao, et al.
Publicado: (2023)

Antimicrobial Activity of Mesenchymal Stem Cells: Current Status and New Perspectives of Antimicrobial Peptide-Based Therapies
por: Alcayaga-Miranda, Francisca, et al.
Publicado: (2017)

Enhanced Metabolite Productivity of Escherichia coli Adapted to Glucose M9 Minimal Medium
por: Rugbjerg, Peter, et al.
Publicado: (2018)

Basal-Like Cell-Conditioned Medium Exerts Anti-Fibrotic Effects In Vitro and In Vivo
por: Khan, Petra, et al.
Publicado: (2022)

Effects of Clostridium beijerinckii and Medium Modifications on Acetone–Butanol–Ethanol Production From Switchgrass
por: Olorunsogbon, Tinuola, et al.
Publicado: (2022)

Immunomodulation of MSCs and MSC-Derived Extracellular Vesicles in Osteoarthritis
por: Zhao, Xige, et al.
Publicado: (2020)

Technological Approaches in the Analysis of Extracellular Vesicle Nucleotide Sequences
por: Tesovnik, Tine, et al.
Publicado: (2021)

Modification of PEG reduces the immunogenicity of biosynthetic gas vesicles
por: Wang, Yuanyuan, et al.
Publicado: (2023)

Engineered extracellular vesicles as therapeutics of degenerative orthopedic diseases
por: Wei, Junyu, et al.
Publicado: (2023)

Culture Medium Supplements Derived from Human Platelet and Plasma: Cell Commitment and Proliferation Support
por: Muraglia, Anita, et al.
Publicado: (2017)

Characterization of a Novel α-Neoagarobiose Hydrolase Capable of Preparation of Medium- and Long-Chain Agarooligosaccharides
por: Jiang, Chengcheng, et al.
Publicado: (2020)

Influence of Unusual Co-substrates on the Biosynthesis of Medium-Chain-Length Polyhydroxyalkanoates Produced in Multistage Chemostat
por: Hanik, Nils, et al.
Publicado: (2019)

Long-Term Continuous Extraction of Medium-Chain Carboxylates by Pertraction With Submerged Hollow-Fiber Membranes
por: Xu, Jiajie, et al.
Publicado: (2021)

Open Culture Ethanol-Based Chain Elongation to Form Medium Chain Branched Carboxylates and Alcohols
por: de Leeuw, Kasper D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hu8o91ofcj0bn29t0troamt79o