Asiatic Acid Induces Endoplasmic Reticulum Stress and Activates the Grp78/IRE1α/JNK and Calpain Pathways to Inhibit Tongue Cancer Growth

Asiatic acid (AA) has been shown to induce apoptotic death in a range of cancers, but the mechanisms whereby it can inhibit tongue cancer growth have yet to be clarified. Herein, we explored the effects of AA on tongue cancer cells and found that it induced their apoptotic death in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Li, Jialin, Chen, Kan, Huang, Jianhua, Chu, Dongqing, Tian, Miaomiao, Huang, Keqiang, Ma, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187906/
https://www.ncbi.nlm.nih.gov/pubmed/34122116
http://dx.doi.org/10.3389/fphar.2021.690612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187906/
https://www.ncbi.nlm.nih.gov/pubmed/34122116
http://dx.doi.org/10.3389/fphar.2021.690612

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