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Attenuated Induction of the Unfolded Protein Response in Adult Human Primary Astrocytes in Response to Recurrent Low Glucose

AIMS/HYPOTHESIS: Recurrent hypoglycaemia (RH) is a major side-effect of intensive insulin therapy for people with diabetes. Changes in hypoglycaemia sensing by the brain contribute to the development of impaired counterregulatory responses to and awareness of hypoglycaemia. Little is known about the...

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Detalles Bibliográficos
Autores principales: Weightman Potter, Paul G., Washer, Sam J., Jeffries, Aaron R., Holley, Janet E., Gutowski, Nick J., Dempster, Emma L., Beall, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187939/
https://www.ncbi.nlm.nih.gov/pubmed/34122346
http://dx.doi.org/10.3389/fendo.2021.671724