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Computational study to discover potent phytochemical inhibitors against drug target, squalene synthase from Leishmania donovani

AIMS: The parasite, Leishmania donovani is responsible for lethal visceral leishmaniasis (VL) in humans. There is a need to investigate novel medicines as antileishmanial drugs, as medication currently introduced for leishmaniasis may cause resistance, serious side-effects, chemical instability and...

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Detalles Bibliográficos
Autores principales: Wadanambi, Padmika Madushanka, Mannapperuma, Uthpali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188062/
https://www.ncbi.nlm.nih.gov/pubmed/34141935
http://dx.doi.org/10.1016/j.heliyon.2021.e07178