Multi‐Arm PEG/Peptidomimetic Conjugate Inhibitors of DR6/APP Interaction Block Hematogenous Tumor Cell Extravasation

The binding of amyloid precursor protein (APP) expressed on tumor cells to death receptor 6 (DR6) could initiate the necroptosis pathway, which leads to necroptotic cell death of vascular endothelial cells (ECs) and results in tumor cells (TCs) extravasation and metastasis. This study reports the fi...

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Detalles Bibliográficos
Autores principales: Wang, Liting, Shen, Qing, Liao, Hongze, Fu, Hao, Wang, Qi, Yu, Jian, Zhang, Wei, Chen, Chuanrong, Dong, Yang, Yang, Xupeng, Guo, Qianqian, Zhang, Jiali, Zhang, Jian, Lin, Houwen, Duan, Yourong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188212/
https://www.ncbi.nlm.nih.gov/pubmed/34105277
http://dx.doi.org/10.1002/advs.202003558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188212/
https://www.ncbi.nlm.nih.gov/pubmed/34105277
http://dx.doi.org/10.1002/advs.202003558

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