Multi‐Arm PEG/Peptidomimetic Conjugate Inhibitors of DR6/APP Interaction Block Hematogenous Tumor Cell Extravasation

The binding of amyloid precursor protein (APP) expressed on tumor cells to death receptor 6 (DR6) could initiate the necroptosis pathway, which leads to necroptotic cell death of vascular endothelial cells (ECs) and results in tumor cells (TCs) extravasation and metastasis. This study reports the fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Liting, Shen, Qing, Liao, Hongze, Fu, Hao, Wang, Qi, Yu, Jian, Zhang, Wei, Chen, Chuanrong, Dong, Yang, Yang, Xupeng, Guo, Qianqian, Zhang, Jiali, Zhang, Jian, Lin, Houwen, Duan, Yourong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188212/
https://www.ncbi.nlm.nih.gov/pubmed/34105277
http://dx.doi.org/10.1002/advs.202003558

Ejemplares similares

Ejemplares similares