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Targeted RNA N (6)‐Methyladenosine Demethylation Controls Cell Fate Transition in Human Pluripotent Stem Cells

Deficiency of the N (6)‐methyladenosine (m(6)A) methyltransferase complex results in global reduction of m(6)A abundance and defective cell development in embryonic stem cells (ESCs). However, it's unclear whether regional m(6)A methylation affects cell fate decisions due to the inability to mo...

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Detalles Bibliográficos
Autores principales: Chen, Xuena, Zhao, Qingquan, Zhao, Yu‐Li, Chai, Guo‐Shi, Cheng, Weisheng, Zhao, Zhiju, Wang, Jia, Luo, Guan‐Zheng, Cao, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188216/
https://www.ncbi.nlm.nih.gov/pubmed/34105279
http://dx.doi.org/10.1002/advs.202003902