Biosynthesis of the sactipeptide Ruminococcin C by the human microbiome: Mechanistic insights into thioether bond formation by radical SAM enzymes

Despite its major importance in human health, the metabolic potential of the human gut microbiota is still poorly understood. We have recently shown that biosynthesis of Ruminococcin C (RumC), a novel ribosomally synthesized and posttranslationally modified peptide (RiPP) produced by the commensal b...

Descripción completa

Detalles Bibliográficos
Autores principales: Balty, Clémence, Guillot, Alain, Fradale, Laura, Brewee, Clémence, Lefranc, Benjamin, Herrero, Christian, Sandström, Corine, Leprince, Jérôme, Berteau, Olivier, Benjdia, Alhosna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188230/
https://www.ncbi.nlm.nih.gov/pubmed/32972973
http://dx.doi.org/10.1074/jbc.RA120.015371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188230/
https://www.ncbi.nlm.nih.gov/pubmed/32972973
http://dx.doi.org/10.1074/jbc.RA120.015371

Ejemplares similares