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HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype
Elucidating the mechanisms underpinning fertilisation is essential to optimising IVF procedures. One of the critical steps involves paternal chromatin reprogramming, in which compacted sperm chromatin packed by protamines is removed by oocyte factors and new histones, including histone H3.3, are inc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188263/ https://www.ncbi.nlm.nih.gov/pubmed/33835048 http://dx.doi.org/10.1530/REP-20-0636 |