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HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype

Elucidating the mechanisms underpinning fertilisation is essential to optimising IVF procedures. One of the critical steps involves paternal chromatin reprogramming, in which compacted sperm chromatin packed by protamines is removed by oocyte factors and new histones, including histone H3.3, are inc...

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Detalles Bibliográficos
Autores principales: Smith, Rowena, Pickering, Sue J, Kopakaki, Anna, Thong, K J, Anderson, Richard A, Lin, Chih-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188263/
https://www.ncbi.nlm.nih.gov/pubmed/33835048
http://dx.doi.org/10.1530/REP-20-0636