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A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adulthood. In vivo, renal tubules are tightly packed, so...

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Detalles Bibliográficos
Autores principales: Myram, Sarah, Venzac, Bastien, Lapin, Brice, Battistella, Aude, Cayrac, Fanny, Cinquin, Bertrand, Cavaniol, Charles, Gropplero, Giacomo, Bonnet, Isabelle, Demolombe, Sophie, Descroix, Stéphanie, Coscoy, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188354/
https://www.ncbi.nlm.nih.gov/pubmed/34124016
http://dx.doi.org/10.3389/fbioe.2021.624553