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A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adulthood. In vivo, renal tubules are tightly packed, so...
Autores principales: | Myram, Sarah, Venzac, Bastien, Lapin, Brice, Battistella, Aude, Cayrac, Fanny, Cinquin, Bertrand, Cavaniol, Charles, Gropplero, Giacomo, Bonnet, Isabelle, Demolombe, Sophie, Descroix, Stéphanie, Coscoy, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188354/ https://www.ncbi.nlm.nih.gov/pubmed/34124016 http://dx.doi.org/10.3389/fbioe.2021.624553 |
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