SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis

The secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein with unexpected immunosuppressive function in myeloid cells. We investigated the role of SPARC in autoimmunity using the pristane-induced model of lupus that, in mice, mimics human systemic lupus erythematosus (SLE)....

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Detalles Bibliográficos
Autores principales: Sangaletti, Sabina, Botti, Laura, Gulino, Alessandro, Lecis, Daniele, Bassani, Barbara, Portararo, Paola, Milani, Matteo, Cancila, Valeria, De Cecco, Loris, Dugo, Matteo, Tripodo, Claudio, Colombo, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188360/
https://www.ncbi.nlm.nih.gov/pubmed/34142027
http://dx.doi.org/10.1016/j.isci.2021.102510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188360/
https://www.ncbi.nlm.nih.gov/pubmed/34142027
http://dx.doi.org/10.1016/j.isci.2021.102510

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