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Modeling muscle regeneration in RNA toxicity mice

RNA toxicity underlies the pathogenesis of disorders such as myotonic dystrophy type 1 (DM1). Muscular dystrophy is a key element of the pathology of DM1. The means by which RNA toxicity causes muscular dystrophy in DM1 is unclear. Here, we have used the DM200 mouse model of RNA toxicity due to the...

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Detalles Bibliográficos
Autores principales: Yadava, Ramesh S, Mandal, Mahua, Giese, Jack M, Rigo, Frank, Bennett, C Frank, Mahadevan, Mani S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188403/
https://www.ncbi.nlm.nih.gov/pubmed/33864373
http://dx.doi.org/10.1093/hmg/ddab108