Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis

Emerging evidence challenges the lens as an immune-privileged organ. Here, we provide a direct mechanism supporting a role of macrophages in lens capsule rupture repair. Posterior lens capsule rupture in a connexin 50 and aquaporin 0 double-knockout mouse model resulted in lens tissue extrusion into...

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Detalles Bibliográficos
Autores principales: Li, Yuting, Li, Zhen, Quan, Yumeng, Cheng, Hongyun, Riquelme, Manuel A., Li, Xiao-Dong, Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188486/
https://www.ncbi.nlm.nih.gov/pubmed/34142044
http://dx.doi.org/10.1016/j.isci.2021.102533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188486/
https://www.ncbi.nlm.nih.gov/pubmed/34142044
http://dx.doi.org/10.1016/j.isci.2021.102533

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