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Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis
Emerging evidence challenges the lens as an immune-privileged organ. Here, we provide a direct mechanism supporting a role of macrophages in lens capsule rupture repair. Posterior lens capsule rupture in a connexin 50 and aquaporin 0 double-knockout mouse model resulted in lens tissue extrusion into...
Autores principales: | Li, Yuting, Li, Zhen, Quan, Yumeng, Cheng, Hongyun, Riquelme, Manuel A., Li, Xiao-Dong, Gu, Sumin, Jiang, Jean X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188486/ https://www.ncbi.nlm.nih.gov/pubmed/34142044 http://dx.doi.org/10.1016/j.isci.2021.102533 |
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