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Activation of cGAS/STING pathway upon paramyxovirus infection

During inflammatory diseases, cancer, and infection, the cGAS/STING pathway is known to recognize foreign or self-DNA in the cytosol and activate an innate immune response. Here, we report that negative-strand RNA paramyxoviruses, Nipah virus (NiV), and measles virus (MeV), can also trigger the cGAS...

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Detalles Bibliográficos
Autores principales: Iampietro, Mathieu, Dumont, Claire, Mathieu, Cyrille, Spanier, Julia, Robert, Jonathan, Charpenay, Aude, Dupichaud, Sébastien, Dhondt, Kévin P., Aurine, Noémie, Pelissier, Rodolphe, Ferren, Marion, Mély, Stéphane, Gerlier, Denis, Kalinke, Ulrich, Horvat, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188492/
https://www.ncbi.nlm.nih.gov/pubmed/34142033
http://dx.doi.org/10.1016/j.isci.2021.102519