Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step

Fluorescent proteins (FPs) have revolutionised the life sciences, but the mechanism of chromophore maturation is still not fully understood. Here we show that incorporation of a photo-responsive non-canonical amino acid within the chromophore stalls maturation of Venus, a yellow FP, at an intermedia...

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Detalles Bibliográficos
Autores principales: Auhim, Husam Sabah, Grigorenko, Bella L., Harris, Tessa K., Aksakal, Ozan E., Polyakov, Igor V., Berry, Colin, Gomes, Gabriel dos Passos, Alabugin, Igor V., Rizkallah, Pierre J., Nemukhin, Alexander V., Jones, D. Dafydd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188506/
https://www.ncbi.nlm.nih.gov/pubmed/34168826
http://dx.doi.org/10.1039/d0sc06693a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188506/
https://www.ncbi.nlm.nih.gov/pubmed/34168826
http://dx.doi.org/10.1039/d0sc06693a

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