Nickel-catalyzed asymmetric reductive cross-coupling of α-chloroesters with (hetero)aryl iodides

An asymmetric reductive cross-coupling of α-chloroesters and (hetero)aryl iodides is reported. This nickel-catalyzed reaction proceeds with a chiral BiOX ligand under mild conditions, affording α-arylesters in good yields and enantioselectivities. The reaction is tolerant of a variety of functional...

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Detalles Bibliográficos
Autores principales: DeLano, Travis J., Dibrell, Sara E., Lacker, Caitlin R., Pancoast, Adam R., Poremba, Kelsey E., Cleary, Leah, Sigman, Matthew S., Reisman, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188512/
https://www.ncbi.nlm.nih.gov/pubmed/34168828
http://dx.doi.org/10.1039/d1sc00822f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188512/
https://www.ncbi.nlm.nih.gov/pubmed/34168828
http://dx.doi.org/10.1039/d1sc00822f

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