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Evaluation of polymer choice on immunogenicity of chitosan coated PLGA NPs with surface-adsorbed pneumococcal protein antigen PspA4Pro

Polymeric nanoparticles (NPs) are recognized as potential delivery vehicles for vaccines. PLGA is a biocompatible polymer synonymous with polymeric NPs, which can be coated with other polymers such as chitosan that has intrinsic adjuvant properties as well as mucoadhesive properties. Numerous modifi...

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Detalles Bibliográficos
Autores principales: Kaneko, Kan, Miyaji, Eliane N., Gonçalves, Viviane M., Ferreira, Daniela M., Solórzano, Carla, MacLoughlin, Ronan, Saleem, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188518/
https://www.ncbi.nlm.nih.gov/pubmed/33675930
http://dx.doi.org/10.1016/j.ijpharm.2021.120407