Histone H3K9 butyrylation is regulated by dietary fat and stress via an Acyl-CoA dehydrogenase short chain-dependent mechanism

OBJECTIVE: We previously reported that β-oxidation enzymes are present in the nucleus in close proximity to transcriptionally active promoters. Thus, we hypothesized that the fatty acid intermediate, butyryl-CoA, is the substrate for histone butyrylation and its abundance is regulated by acyl-CoA de...

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Detalles Bibliográficos
Autores principales: Yang, Zhi, He, Minzhen, Austin, Julianne, Pfleger, Jessica, Abdellatif, Maha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188563/
https://www.ncbi.nlm.nih.gov/pubmed/33989779
http://dx.doi.org/10.1016/j.molmet.2021.101249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188563/
https://www.ncbi.nlm.nih.gov/pubmed/33989779
http://dx.doi.org/10.1016/j.molmet.2021.101249

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