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Evaluation of fully-functionalized diazirine tags for chemical proteomic applications

The use of photo-affinity reagents for the mapping of noncovalent small molecule–protein interactions has become widespread. Recently, several ‘fully-functionalized’ (FF) chemical tags have been developed wherein a photoactivatable capture group, an enrichment handle, and a functional group for synt...

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Detalles Bibliográficos
Autores principales: Conway, Louis P., Jadhav, Appaso M., Homan, Rick A., Li, Weichao, Rubiano, Juanita Sanchez, Hawkins, Richard, Lawrence, R. Michael, Parker, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188597/
https://www.ncbi.nlm.nih.gov/pubmed/34168837
http://dx.doi.org/10.1039/d1sc01360b