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Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions

We describe the extended endothelial cell culture method (EECM) for the differentiation of human pluripotent stem cells (hPSCs) into brain microvascular endothelial cell (BMEC)-like cells. EECM-BMEC-like cells resemble primary human BMECs in morphology, molecular junctional architecture, and diffusi...

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Detalles Bibliográficos
Autores principales: Nishihara, Hideaki, Gastfriend, Benjamin D., Kasap, Pelin, Palecek, Sean P., Shusta, Eric V., Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188617/
https://www.ncbi.nlm.nih.gov/pubmed/34151293
http://dx.doi.org/10.1016/j.xpro.2021.100563