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Ginkgolide J protects human synovial cells SW982 via suppression of p38-dependent production of pro-inflammatory mediators

Fibroblast-like synoviocytes (FLS) in the synovial lining play a key role in the pathological process of rheumatoid arthritis (RA), which produce pro-inflammatory mediators to perpetuate inflammation and proteases to contribute to cartilage destruction. Ginkgolide J (GJ) is a subclass of ginkgolides...

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Detalles Bibliográficos
Autores principales: Zhao, Yujie, Chen, Yuan, Wang, Jiayi, Zhu, Xue, Wang, Ke, Li, Yue, Zhou, Fanfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188640/
https://www.ncbi.nlm.nih.gov/pubmed/34080024
http://dx.doi.org/10.3892/mmr.2021.12194