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Ginkgolide J protects human synovial cells SW982 via suppression of p38-dependent production of pro-inflammatory mediators
Fibroblast-like synoviocytes (FLS) in the synovial lining play a key role in the pathological process of rheumatoid arthritis (RA), which produce pro-inflammatory mediators to perpetuate inflammation and proteases to contribute to cartilage destruction. Ginkgolide J (GJ) is a subclass of ginkgolides...
Autores principales: | Zhao, Yujie, Chen, Yuan, Wang, Jiayi, Zhu, Xue, Wang, Ke, Li, Yue, Zhou, Fanfan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188640/ https://www.ncbi.nlm.nih.gov/pubmed/34080024 http://dx.doi.org/10.3892/mmr.2021.12194 |
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