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Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing

Bacterial transposons propagate through either non-replicative (cut-and-paste) or replicative (copy-and-paste) pathways, depending on how the mobile element is excised from its donor source. In the well-characterized E. coli transposon Tn7, a heteromeric TnsA-TnsB transposase directs cut-and-paste t...

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Detalles Bibliográficos
Autores principales: Vo, Phuc Leo H., Acree, Christopher, Smith, Melissa L., Sternberg, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188705/
https://www.ncbi.nlm.nih.gov/pubmed/34103093
http://dx.doi.org/10.1186/s13100-021-00242-2