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Simple rapid in vitro screening method for SARS-CoV-2 anti-virals that identifies potential cytomorbidity-associated false positives

BACKGROUND: The international SARS-CoV-2 pandemic has resulted in an urgent need to identify new anti-viral drugs for treatment of COVID-19. The initial step to identifying potential candidates usually involves in vitro screening that includes standard cytotoxicity controls. Under-appreciated is tha...

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Detalles Bibliográficos
Autores principales: Yan, Kexin, Rawle, Daniel J., Le, Thuy T., Suhrbier, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188739/
https://www.ncbi.nlm.nih.gov/pubmed/34107996
http://dx.doi.org/10.1186/s12985-021-01587-z