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Effects of substrate stiffness and actin velocity on in silico fibronectin fibril morphometry and mechanics

Assembly of the extracellular matrix protein fibronectin (FN) into insoluble, viscoelastic fibrils is a critical step during embryonic development and wound healing; misregulation of FN fibril assembly has been implicated in many diseases, including fibrotic diseases and cancer. We have previously d...

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Detalles Bibliográficos
Autores principales: Weinberg, Seth H., Saini, Navpreet, Lemmon, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189481/
https://www.ncbi.nlm.nih.gov/pubmed/34106923
http://dx.doi.org/10.1371/journal.pone.0248256