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TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2

Antiviral therapeutics are a front-line defense against virally induced diseases. Because viruses frequently mutate to escape direct inhibition of viral proteins, there is interest in targeting the host proteins that the virus must co-opt to complete its replication cycle. However, a detailed unders...

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Detalles Bibliográficos
Autores principales: Trimarco, Joseph D., Heaton, Brook E., Chaparian, Ryan R., Burke, Kaitlyn N., Binder, Raquel A., Gray, Gregory C., Smith, Clare M., Menachery, Vineet D., Heaton, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189496/
https://www.ncbi.nlm.nih.gov/pubmed/34043740
http://dx.doi.org/10.1371/journal.ppat.1009599