Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy

Treating macaques with an anti-α4β7 antibody under the umbrella of combination antiretroviral therapy (cART) during early SIV infection can lead to viral remission, with viral loads maintained at < 50 SIV RNA copies/ml after removal of all treatment in a subset of animals. Depletion of CD8(+) lym...

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Detalles Bibliográficos
Autores principales: Wells, Chad R., Cao, Youfang, Durham, David P., Byrareddy, Siddappa N., Ansari, Aftab A., Ruddle, Nancy H., Townsend, Jeffrey P., Galvani, Alison P., Perelson, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189501/
https://www.ncbi.nlm.nih.gov/pubmed/34106916
http://dx.doi.org/10.1371/journal.pcbi.1009031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189501/
https://www.ncbi.nlm.nih.gov/pubmed/34106916
http://dx.doi.org/10.1371/journal.pcbi.1009031

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