Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis

Recent studies have identified impaired type 2 alveolar epithelial cell (ATII) renewal in idiopathic pulmonary fibrosis (IPF) human organoids and severe fibrosis when ATII is defective in mice. ATIIs function as progenitor cells and require supportive signals from the surrounding mesenchymal cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Ting, Kulur, Vrishika, Liu, Ningshan, Deng, Nan, Wang, Yizhou, Rowan, Simon Coyle, Yao, Changfu, Huang, Guanling, Liu, Xue, Taghavifar, Forough, Liang, Jiurong, Hogaboam, Cory, Stripp, Barry, Chen, Peter, Jiang, Dianhua, Noble, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189579/
https://www.ncbi.nlm.nih.gov/pubmed/34108218
http://dx.doi.org/10.1126/sciadv.abg6005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189579/
https://www.ncbi.nlm.nih.gov/pubmed/34108218
http://dx.doi.org/10.1126/sciadv.abg6005

Ejemplares similares