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Testicular germ cell–specific lncRNA, Teshl, is required for complete expression of Y chromosome genes and a normal offspring sex ratio

Heat shock factor 2 (HSF2) regulates the transcription of the male-specific region of the mouse Y chromosome long arm (MSYq) multicopy genes only in testes, but the molecular mechanism underlying this tissue specificity remains largely unknown. Here, we report that the testicular germ cell–specific...

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Detalles Bibliográficos
Autores principales: Hong, Seong Hyeon, Han, Gwidong, Lee, Seung Jae, Cocquet, Julie, Cho, Chunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189594/
https://www.ncbi.nlm.nih.gov/pubmed/34108217
http://dx.doi.org/10.1126/sciadv.abg5177