A trispecific killer engager molecule against CLEC12A effectively induces NK cell mediated killing of AML cells

The low five-year survival rate for patients with acute myeloid leukemia (AML), primarily caused due to disease relapse, emphasizes the need for better therapeutic strategies. Disease relapse is facilitated by leukemic stem cells (LSCs) that are resistant to standard chemotherapy and promote tumor g...

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Detalles Bibliográficos
Autores principales: Arvindam, Upasana Sunil, van Hauten, Paulien M.M., Schirm, Dawn, Schaap, Nicolaas, Hobo, Willemijn, Blazar, Bruce R., Vallera, Daniel A., Dolstra, Harry, Felices, Martin, Miller, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189652/
https://www.ncbi.nlm.nih.gov/pubmed/33097838
http://dx.doi.org/10.1038/s41375-020-01065-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189652/
https://www.ncbi.nlm.nih.gov/pubmed/33097838
http://dx.doi.org/10.1038/s41375-020-01065-5

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