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Molecular Basis for the Interactions of Human Thioredoxins with Their Respective Reductases

The mammalian cytosolic thioredoxin (Trx) system consists of Trx1 and its reductase, the NADPH-dependent seleno-enzyme TrxR1. These proteins function as electron donor for metabolic enzymes, for instance in DNA synthesis, and the redox regulation of numerous processes. In this work, we analysed the...

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Detalles Bibliográficos
Autores principales: Hossain, Md Faruq, Bodnar, Yana, Klein, Calvin, Salas, Clara Ortegón, Arnér, Elias S. J., Gellert, Manuela, Lillig, Christopher Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189816/
https://www.ncbi.nlm.nih.gov/pubmed/34122725
http://dx.doi.org/10.1155/2021/6621292