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Non-invasive and high-throughput interrogation of exon-specific isoform expression

Expression of exon-specific isoforms from alternatively spliced mRNA is a fundamental mechanism that substantially expands the proteome of a cell. However, conventional methods to assess alternative splicing are either consumptive and work-intensive or do not quantify isoform expression longitudinal...

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Detalles Bibliográficos
Autores principales: Truong, Dong-Jiunn Jeffery, Phlairaharn, Teeradon, Eßwein, Bianca, Gruber, Christoph, Tümen, Deniz, Baligács, Enikő, Armbrust, Niklas, Vaccaro, Francesco Leandro, Lederer, Eva-Maria, Beck, Eva Magdalena, Geilenkeuser, Julian, Göppert, Simone, Krumwiede, Luisa, Grätz, Christian, Raffl, Gerald, Schwarz, Dominic, Zirngibl, Martin, Živanić, Milica, Beyer, Maren, Körner, Johann Dietmar, Santl, Tobias, Evsyukov, Valentin, Strauß, Tabea, Schwarz, Sigrid C., Höglinger, Günter U., Heutink, Peter, Doll, Sebastian, Conrad, Marcus, Giesert, Florian, Wurst, Wolfgang, Westmeyer, Gil Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189919/
https://www.ncbi.nlm.nih.gov/pubmed/34083785
http://dx.doi.org/10.1038/s41556-021-00678-x