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Autophagy-Mediated Clearance of Free Genomic DNA in the Cytoplasm Protects the Growth and Survival of Cancer Cells

The cGAS (GMP-AMP synthase)-mediated senescence-associated secretory phenotype (SASP) and DNA-induced autophagy (DNA autophagy) have been extensively investigated in recent years. However, cGAS-mediated autophagy has not been elucidated in cancer cells. The described investigation revealed that acti...

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Detalles Bibliográficos
Autores principales: Yao, Mengfei, Wu, Yaqian, Cao, Yanan, Liu, Haijing, Ma, Ningning, Chai, Yijie, Zhang, Shuang, Zhang, Hong, Nong, Lin, Liang, Li, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189927/
https://www.ncbi.nlm.nih.gov/pubmed/34123836
http://dx.doi.org/10.3389/fonc.2021.667920