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Efficacy, Safety, and Exposure of Apixaban in Patients with High Body Weight or Obesity and Venous Thromboembolism: Insights from AMPLIFY

INTRODUCTION: As a result of limited clinical data, guidelines do not recommend the use of non-vitamin K antagonist oral anticoagulants in patients who weigh > 120 kg or have a body mass index (BMI) > 40 kg/m(2). METHODS: This post hoc analysis of the AMPLIFY trial evaluated the efficacy (veno...

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Detalles Bibliográficos
Autores principales: Cohen, Alexander T., Pan, Sharon, Byon, Wonkyung, Ilyas, Bushra S., Taylor, Thomas, Lee, Theodore C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189985/
https://www.ncbi.nlm.nih.gov/pubmed/33890242
http://dx.doi.org/10.1007/s12325-021-01716-8