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Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study

BACKGROUND: Insulin is the key regulator of glucose metabolism, but it is difficult to dissect direct insulin from glucose-induced effects. We aimed to investigate the effects of hyperinsulemia on metabolomic measures under euglycemic conditions in nondiabetic participants. METHODS: We assessed conc...

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Detalles Bibliográficos
Autores principales: Wang, Wenyi, van Dijk, Ko Willems, Wijsman, Carolien A., Rozing, Maarten P., Mooijaart, Simon P., Beekman, Marian, Slagboom, P. Eline, Jukema, J. Wouter, Noordam, Raymond, van Heemst, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190027/
https://www.ncbi.nlm.nih.gov/pubmed/34106350
http://dx.doi.org/10.1007/s11306-021-01806-2