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Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM-based single-cell force spectroscopy

Cadherins enable intercellular adherens junctions to withstand tensile forces in tissues, e.g. generated by intracellular actomyosin contraction. In-vitro single molecule force spectroscopy experiments can reveal cadherin–cadherin extracellular region binding dynamics such as bond formation and stre...

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Detalles Bibliográficos
Autores principales: Viji Babu, Prem Kumar, Mirastschijski, Ursula, Belge, Ganzanfer, Radmacher, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190030/
https://www.ncbi.nlm.nih.gov/pubmed/33880610
http://dx.doi.org/10.1007/s00249-021-01536-2