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Multiomics analysis reveals CT83 is the most specific gene for triple negative breast cancer and its hypomethylation is oncogenic in breast cancer

Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer (BrC) subtype lacking effective therapeutic targets currently. The development of multi-omics databases facilities the identification of core genes for TNBC. Using TCGA-BRCA and METABRIC datasets, we identified CT83 as the mos...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Gao, Dan, Huo, Jinlong, Qu, Rui, Guo, Youming, Hu, Xiaochi, Luo, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190062/
https://www.ncbi.nlm.nih.gov/pubmed/34108519
http://dx.doi.org/10.1038/s41598-021-91290-4