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Central nervous system (CNS) transcriptomic correlates of human immunodeficiency virus (HIV) brain RNA load in HIV-infected individuals

To generate new mechanistic hypotheses on the pathogenesis and disease progression of neuroHIV and identify novel therapeutic targets to improve neuropsychological function in people with HIV, we investigated host genes and pathway dysregulations associated with brain HIV RNA load in gene expression...

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Detalles Bibliográficos
Autores principales: Sanna, Pietro Paolo, Fu, Yu, Masliah, Eliezer, Lefebvre, Celine, Repunte-Canonigo, Vez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190104/
https://www.ncbi.nlm.nih.gov/pubmed/34108514
http://dx.doi.org/10.1038/s41598-021-88052-7