Cargando…

Structural insight on assembly-line catalysis in terpene biosynthesis

Fusicoccadiene synthase from Phomopsis amygdali (PaFS) is a unique bifunctional terpenoid synthase that catalyzes the first two steps in the biosynthesis of the diterpene glycoside Fusicoccin A, a mediator of 14-3-3 protein interactions. The prenyltransferase domain of PaFS generates geranylgeranyl...

Descripción completa

Detalles Bibliográficos
Autores principales: Faylo, Jacque L., van Eeuwen, Trevor, Kim, Hee Jong, Gorbea Colón, Jose J., Garcia, Benjamin A., Murakami, Kenji, Christianson, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190136/
https://www.ncbi.nlm.nih.gov/pubmed/34108468
http://dx.doi.org/10.1038/s41467-021-23589-9