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Structural insight on assembly-line catalysis in terpene biosynthesis

Fusicoccadiene synthase from Phomopsis amygdali (PaFS) is a unique bifunctional terpenoid synthase that catalyzes the first two steps in the biosynthesis of the diterpene glycoside Fusicoccin A, a mediator of 14-3-3 protein interactions. The prenyltransferase domain of PaFS generates geranylgeranyl...

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Detalles Bibliográficos
Autores principales:	Faylo, Jacque L., van Eeuwen, Trevor, Kim, Hee Jong, Gorbea Colón, Jose J., Garcia, Benjamin A., Murakami, Kenji, Christianson, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190136/ https://www.ncbi.nlm.nih.gov/pubmed/34108468 http://dx.doi.org/10.1038/s41467-021-23589-9

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