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Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
A hallmark of chromosome organization is the partition into transcriptionally active A and repressed B compartments, and into topologically associating domains (TADs). Both structures were regarded to be absent from the inactive mouse X chromosome, but to be re-established with transcriptional react...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190187/ https://www.ncbi.nlm.nih.gov/pubmed/34108480 http://dx.doi.org/10.1038/s41467-021-23610-1 |